Emmanuel Eric Pazo

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Macular function measured by Nidek MP-3 microperimeter in normal Chinese individuals across age groups

Dan Hu, Q. Wang, Qingcui Liu, Emmanuel Eric Pazo, Zhe Liu, Shuang Wu, Wen Zhang, Xing Yan, Bo Yu

PeerJ, 2025 · article · doi:10.7717/peerj.19961 · Open access (CC BY)

Retina & vascular imaging

Abstract

Background: Microperimetry has emerged as a tool for assessing retinal function, especially macular function in recent years. In this study, the MP-3, a widely adopted device, was employed to analyze macular sensitivity and fixation stability across various age groups. Methods: The research involved evaluating the macular sensitivity and fixation stability of 182 healthy eyes free from ocular disorders. The relationship between macular sensitivity, fixation pattern, and age was determined through generalized estimating equations. Results: Macular sensitivity and percentage of fixation stability within 2° and 4° were measured for 182 eyes (mean age: 45.24 ± 17.03 years) using MP-3. The mean macular sensitivity was 29.5 ± 1.6, while the mean percentage of fixation points within a 2° circle was 93.0 ± 7.5%, and within a 4° circle was 98.3 ± 2.8%. Macular sensitivity, as well as the percentage of fixation points within the central 2° and 4° areas, tended diminish with advancing age. Conclusion: In conclusion, among normal subjects, macular sensitivity and fixation values decrease with age. MP-3 emerges as a reliable instrument for measuring macular function.

Keywords: macular function; microperimetry; macular sensitivity; fixation stability; age-related decline; retinal function; healthy eyes; Chinese population

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How to cite

Hu, D., Wang, Q., Liu, Q., Pazo, E. E., Liu, Z., Wu, S., Zhang, W., Yan, X., Yu, B. (2025). Macular function measured by Nidek MP-3 microperimeter in normal Chinese individuals across age groups. PeerJ. https://doi.org/10.7717/peerj.19961

@article{hu2025macular,
  title = {{Macular function measured by Nidek MP-3 microperimeter in normal Chinese individuals across age groups}},
  author = {Hu, Dan and Wang, Q. and Liu, Qingcui and Pazo, Emmanuel Eric and Liu, Zhe and Wu, Shuang and Zhang, Wen and Yan, Xing and Yu, Bo},
  journal = {PeerJ},
  year = {2025},
  doi = {10.7717/peerj.19961},
  url = {https://doi.org/10.7717/peerj.19961},
}

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