Emmanuel Eric Pazo

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The Efficacy and Safety of YAG Laser Vitreolysis for Symptomatic Vitreous Floaters of Complete PVD or Non-PVD

Tiezhu Lin, Tongtong Li, Xinmei Zhang, Yan-Nian Hui, Salissou Moutari, Emmanuel Eric Pazo, Guangzheng Dai, Lijun Shen

Ophthalmology and Therapy, 2021 · article · doi:10.1007/s40123-021-00422-6 · cited by 23 · Open access (CC BY-NC)

Retina & vascular imaging

Abstract

INTRODUCTION: To evaluate and compare the efficacy and safety of YAG laser vitreolysis in treating symptomatic vitreous floaters of complete posterior vitreous detachment (PVD) and non-PVD. METHODS: In this prospective cohort study, 51 eyes with symptomatic floaters were treated with YAG laser vitreolysis. Participants were divided into complete PVD and non-PVD groups. Objective visual quality measures including the Strehl ratio (SR), internal spherical aberration (SA), internal comatic aberration (CA), internal high-order aberration (HOA), area ratio of modulation transfer function (MTFa) and Vitreous Floaters Symptom Questionnaire (VFSQ-13) scores were used to compare the efficacy of YAG laser vitreolysis treatment between two groups. RESULTS: The mean age of all patients was 56.80 ± 10.82 years old. In total, 36 of 51 (70.59%; 95% CI 58.10-83.10) patients reported their symptoms as significant or complete improvement after YAG laser vitreolysis treatment. Post-treatment MTFa, internal SA and internal HOA were significantly better compared to baseline (26.19 ± 14.73 vs. 29.19 ± 17.98, p = 0.013; 0.05 ± 0.05 vs. 0.04 ± 0.04, p = 0.031 and 0.23 ± 0.22 vs. 0.16 ± 0.07, p = 0.044; respectively) in all eyes. Twenty-nine of 51 (56.86%) eyes had floaters of non-PVD type. Significant or complete subjective improvements in the PVD group and non-PVD group were 72.73% and 68.97% (p = 0.344), respectively. CONCLUSIONS: Improved subjective and objective visual quality in participants with symptomatic floaters following YAG laser vitreolysis was found in both groups. The efficacy of YAG laser vitreolysis was comparable in floaters of complete PVD and non-PVD types.

Keywords: vitreous floaters; posterior vitreous detachment; visual quality; higher-order aberrations; modulation transfer function; Strehl ratio; treatment efficacy and safety

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How to cite

Lin, T., Li, T., Zhang, X., Hui, Y., Moutari, S., Pazo, E. E., Dai, G., Shen, L. (2021). The Efficacy and Safety of YAG Laser Vitreolysis for Symptomatic Vitreous Floaters of Complete PVD or Non-PVD. Ophthalmology and Therapy. https://doi.org/10.1007/s40123-021-00422-6

@article{lin2021the,
  title = {{The Efficacy and Safety of YAG Laser Vitreolysis for Symptomatic Vitreous Floaters of Complete PVD or Non-PVD}},
  author = {Lin, Tiezhu and Li, Tongtong and Zhang, Xinmei and Hui, Yan-Nian and Moutari, Salissou and Pazo, Emmanuel Eric and Dai, Guangzheng and Shen, Lijun},
  journal = {Ophthalmology and Therapy},
  year = {2021},
  doi = {10.1007/s40123-021-00422-6},
  url = {https://doi.org/10.1007/s40123-021-00422-6},
}

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